Research
Soon Lau PhD
Dr Soon Lau is a keen and active researcher. He completed a PhD at the University of Sydney in 2023 in split liver transplantation and ex-vivo machine perfusion and pioneered a world-first technique of liver splitting during machine perfusion. He has presented at conferences nationally and internationally and his work was recently published in the prestigious Nature Communications.

Research Awards
Peter Bancroft Prize for Research Work - 2024
Awarded to PhD (Medicine) candidates for passing thesis examination without amendment.
Faculty of Medicine and Health, University of Sydney
Wiley Top Cited Article 2022-2023
Artificial Organs: Long-term normothermic perfusion of human livers for longer than 12 days
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Finalist and Winner of Health Research Award 2023
25th Anniversary NSW Health Awards
Achieving the Unrealised Potential of Transplantation
NSW Health Awards 2023
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Mentee-Mentor Award, The Transplantation Society (TTS)
29th International Congress of the Transplantation Society (TTS 2022)
Buenos Aires, Argentina,
Early Career Researchers Award (Basic Science)
Finalist in the President’s Prize Symposium
40th TSANZ Annual Scientific Meeting
Adelaide, Australia
Rising Star Award, International Liver Transplantation Society (ILTS)
2022 International Congress of ILTS, ELITA and LICAGE
Istanbul, Turkey
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Finalist and Winner of the Inaugural ANZ Chapter of the ACS Surgical Forum
Royal Australasian College of Surgeons 90th Annual Scientific Congress 2022, Brisbane
Royal Prince Alfred Hospital 2021 President’s Prize for Laboratory Research
Royal Prince Alfred Hospital
Publications
Huang, J., Lau, N-S., Ly, M., Babekuhl, D., Yousif, P., Liu, K., McCaughan, G., Crawford, M., Pulitano, C. Incorporating a Haemodialysis Filter into a Commercial Normothermic Perfusion System to Facilitate Long-term Preservation of Human Split-Livers. Artificial Organs. 2024 Sep;48(9):1008-1017.
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Ly M, Lau NS, Dennis C, Chen J, Risbey C, Tan S, Chen R, Wang C, Gorrell MD, McKenzie C, Kench JG, Liu K, McCaughan GW, Crawford M, Pulitano C. Long-term ex situ normothermic machine perfusion allows regeneration of human livers with severe bile duct injury. Am J Transplant. 2024 Jul 24:S1600-6135(24)00442-8. Epub ahead of print.
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Risbey CWG, Lau NS, Pulitano C. The importance of developing viability criteria to assess liver grafts undergoing multi-week normothermic perfusion. J Hepatol. 2024 Jul 20:S0168-8278(24)02420-6. Epub ahead of print.
Jain A, Lau NS. Liver Transplantation in Colorectal Cancer With Unresectable Liver Metastases: Disease Biology Cannot Be Ignored. J Clin Oncol. 2024 Jul 8:JCO2400619. Epub ahead of print.
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Risbey CWG, Lau N-S, Niu A, Zhang WB, Crawford M, Pulitano C. Return of the cold: How hypothermic oxygenated machine perfusion is changing liver transplantation. Transplantation Reviews. 2024;38(3):100853.
Satchithanandha V, Lau NS, Huynh R, Sandroussi C. The silent stent ascent: asymptomatic retrograde migration of pancreatic duct stent post-pancreaticoduodenectomy. International Surgery Journal. 2024 Apr 29;11(5):832-4.
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Polikarpova, A., Lau, N-S., Coker, D., Spontaneous pneumomediastinum. Single centre experience and literature review. Int Surg J. 2024 Apr;11(4):606-611
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Cabanes-Creus, M., Liao, S., Navarro, R., Knight, D., Nazareth, D., Lau, N., Ly, M., Zhu, E., Roca-Pinilla, R., Delgado, R., Baltazar, G., Westhaus, A., Merjane, J., Crawford, M., McCaughan, G., Unzu, C., Gonzalez-Aseuinolaza, G., Alexander, I., Pulitano, C., Lisowski, L. Harnessing the power of whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation. Nature Communications. 2024;15(1):1876.
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Franco, N., Lau, N-S., Liu, W., Rahim, A., Fadia, M., Chua, YJ., Jain, A., Yip, D., Gananadha, S. Outcomes of patients with gallbladder cancer presenting with acute cholecystitis. Langenbecks Arch Surg. 2024; 409, 73.
Polikarpova, A., Lau, N-S., Yeo, D., Cystic duct remnant - duodenal fistula following laparoscopic cholecystectomy. A case report and literature review. Reports. 2024; 7, 16.
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Lau, N., Ly, M., Ewenson, K., Toomath, S., Ly, H., Mestrovic, N., Liu, K., McCaughan, G., Crawford, M., Pulitano, C. Indocyanine Green: A Novel Marker for Assessment of Graft Quality During Ex-Vivo Normothermic Machine Perfusion of Human Livers. Artif Organs. 2024 May;48(5):472-483.
Featured as the cover image for Artificial Organs: Volume 48, Issue 5. http://dx.doi.org/10.1111/aor.14696
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Lau, N., Ly, M., Dennis, C., Jacques, A., Cabanes-Creus, M., Toomath, S., Huang, J., Mestrovic, N., Yousif, P., Chanda, S., Wang, C., Lisowski, L., Liu, K., Kench, J., McCaughan, G., Crawford, M., Pulitano, C. Long-term Ex-Vivo Normothermic Perfusion of Human Split Livers. A Unique Model to Study New Therapeutics and Increase the Number of Available Organs. Nature Communications. 2023;14, 4755
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Ng WR, Lau N-S, Fadia M, Gananadha S. IgG4-related sclerosing cholangitis mimicking cholangiocarcinoma. Journal of Surgical Case Reports. 2023;2023(11)
Satchithanandha V, Lau N-S, Galevska A, Sandroussi C. Bouveret syndrome: two approaches one stone. Journal of Surgical Case Reports. 2023;2023(10)
Ly, M., Lau, N., McKenzie, C., Kench, J., Majumdar, A., Liu, K., McCaughan, G., Crawford, M., Pulitano, C. Histological Assessment of the Bile Duct before Liver Transplantation: Does the Bile Duct Injury Score Predict Biliary Strictures? J Clin Med. 2023;12(21):6793
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Lau, N., Ly, M., Dennis, C., Toomath, S., Huang, JL., Huang, J., Ly, H., Chanda, S., Marinelli, T., Davis, R., Liu, K., McCaughan, G., Crawford, M., Pulitano, C. Microbial Contamination During Long Term Ex-Vivo Normothermic Machine Perfusion of Human Livers. Transplantation. 2023;10, 1097
Lau, N., Ly, M., Dennis, C., Ewenson, K., Ly, H., Huang, JL, Cabanes-Creus, M., Chanda, S., Wang, C., Lisowski, L., Liu, K., Kench, J., McCaughan, G., Crawford, M., Pulitano, C. Liver Splitting During Normothermic Machine Perfusion: A Novel Method to Combine the Advantages of Both In-Situ and Ex-Vivo Techniques. HPB. 2023;25(5), 543-555
Ealing IV, Lau NS, Cheung D, Peruch S, Agostinho N, Crawford M, Pulitano C. Safety of laparoscopic repair of incisional hernias in liver transplant recipients. Clin Transplant. 2023:e14969.
Hall C, Amatya S, Shanmugasundaram R, Lau NS, Beenen E, Gananadha S. Intraoperative Cholangiography in Laparoscopic Cholecystectomy: A Systematic Review and Meta-Analysis. JSLS: Journal of the Society of Laparoendoscopic Surgeons. 2023;27(1).
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Drahman A, Ngee-Soon SL, Crawford M. Prophylactic alpha-blockade for prevention of post-operative urinary retention after inguinal hernia repair: a systematic review and meta-analysis. Hernia: the journal of hernias and abdominal wall surgery. 2023;1-11
Ly M, Lau N-S, McKenzie C, Kench JG, McCaughan G, Crawford M, Pulitano C. Does an Additional Bile Duct Flush With Low-viscosity Preservation Solution Reduce Bile Duct Injury? A Single-blinded Randomized Clinical Trial. Transplantation Direct. 2023;9(3):e1443.
Brodaric AM, Lau N-S, Sandroussi C. Gastric remnant perforation after single anastomosis gastric bypass. J Case Rep Images Surg 2023;9(1):9–12.
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Sidhu, K., Seyfi, D., Lau, N., Yeo, D. (2022). The rare case of oesophago-pericardial fistula secondary to pulmonary tuberculosis. J Surg Case Rep 2022;9:1-3
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Lau, N., Ly, M., Dennis, C., Liu, K., Kench, J., Crawford, M., Pulitano, C. (2022). Long-Term Normothermic Perfusion of Human Livers for Longer Than 12 Days. Artif Organs. 2022;46:2504-2510
Wiley Top Cited Article 2022-2023
Lau, N., Ly, M., Liu, K., Majumdar, A., Strasser, S., Biswas, R., McCaughan, G., Crawford, M., Pulitano, C. (2022). Is it Safe to Expand the Indications for Split Liver Transplantation in Adults? A Single-Centre Analysis of 155 In-Situ Splits. Clin Transplant. 2022;36(7):e14673
Ly, M., Lau, N., McKenzie, C., Kench, J., McCaughan, G., Crawford, M., Pulitano, C (2022). The Delay Of Arterialization After Initial Portal Reperfusion More Than Warm Ischemia Time May Determine Ischemic-Type Biliary Injury. Transplantation. 2022;106(2):e167-e168
Lau, N., Ly, M., Liu, K., Majumdar, A., McCaughan, G., Crawford, M., Pulitano, C. (2022). Current and potential applications for indocyanine green in liver transplantation. Transplantation. 2022;106(7):1339-1350
Lau, N., Ly, M., Jacques, A., Ewenson, K., Mestrovic, N., Almoflihi, A., Koutalistras, N., Liu, K., Kench, J., McCaughan, G., Crawford, M., Pulitano, C. (2021) Prolonged Ex-Vivo Normothermic Perfusion of Split Livers: An Innovative Approach To Increase The Number of Available Grafts. Transplant Direct. 2021;7(10):e763
Lau, N., Liu, K., McCaughan, G., Crawford, M., Pulitano, C. (2021). Are split liver grafts a suitable option in high-risk liver transplant recipients? Curr Opin Organ Transplant. 2021;26(6):675-680.
Xu, J., D’Souza, K., Lau, N., Leslie, S., Lee, T., Yao, J., Lam, S., Sandroussi, C., Chadban, S., Ying, T., Pleass, H., Laurence, J. (2021). Staged versus concurrent native nephrectomy and renal transplantation in patients with Autosomal Dominant Polycystic Kidney Disease: A systematic review. Transplant Rev (Orlando). 2021;100652.
Lau, N., Liu, K., Almoflihi, A., McCaughan, G., Crawford, M., Pulitano, C. (2021). Liberal use of interposition grafts for arterial reconstruction is safe and effective in adult split liver transplantation. Transplant Direct. 2021;7(8):e735.
Lau, N., Jacques, A., McCaughan, G., Crawford, M., Liu, K., Pulitano, C. (2021). Addressing the challenges of split liver transplantation through technical advances. A systematic review. Transplant Rev (Orlando). 2021;35(3):100627.
Lau, N., Crawford, M., Sandroussi, C. (2020). Surgical management of symptomatic right-sided Bochdalek hernias in adults: when is a minimally invasive approach appropriate? ANZ J Surg. 2020;90(6):1075-1079.
Lam, S., Lau, N., Laurence, J., Verran, D. (2019). Surgical site infections complicating the use of negative pressure wound therapy in renal transplant recipients. Case Rep Transplant. 2019:2452857.
Lau, N., Ahmadi, N., Verran, D. (2019). Abdominal wall complications following renal transplantation in adult recipients – factors associated with interventional management in one unit. BMC Surg. 2019;19(1):10.
Lau, N., Gorrie, C., Chia, J., Bilston, L., & Clarke, E. (2013). Severity of spinal cord injury in adult and infant rats following vertebral dislocation depends on displacement but not speed. J Neurotrauma. 2013;30(15):1361-1373.